GLP1 (S)
A research-grade Glucagon-Like Peptide-1 (GLP−1) receptor agonist. This peptide is at the forefront of metabolic science, studied for its powerful effects on glucose homeostasis, appetite regulation, and promoting a feeling of satiety, making it a key compound in weight management research.
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What is GLP1 (S)?
Overview
GLP1 (S) is a catalog shorthand commonly used for semaglutide, a long-acting GLP-1 receptor agonist.
In research environments, semaglutide is used to study GLP-1R pharmacology, receptor signaling, and incretin-pathway biology in controlled experimental models.
Key identifiers
- Name: Semaglutide
- FDA substance registry: GINAS: Semaglutide
- CAS (commonly listed): 910463-68-2
- Registry link: PubChem: Semaglutide
Mechanistic context (research framing)
FDA labeling describes semaglutide as a human GLP-1 receptor agonist (GLP-1 analog).
A key “protraction” mechanism is albumin binding, enabled by fatty-acid side-chain modification (as described in labeling).
Research applications
- GLP-1R receptor assays: potency/efficacy, signaling kinetics, pathway bias (assay-dependent)
- Second messenger readouts: commonly cAMP-linked GPCR outputs
- Comparative profiling: benchmarking vs other GLP-1R agonists or multi-agonists in standardized panels
Human-use context (background only)
Semaglutide is the active ingredient in FDA-approved medicines including Ozempic (type 2 diabetes) and Wegovy (chronic weight management).
This is included strictly as scientific background and does not imply intended human use of RUO material.
Form, documentation & storage
- Form: often supplied as lyophilized powder for research workflows (confirm on COA)
- Documentation: use the lot COA for identity/purity and traceability
- General storage: sealed, dry, protected from light; follow SOPs and COA guidance
RUO disclaimer
For Research Use Only. Not for human or veterinary use. Not for diagnostic or therapeutic purposes.
Molecular Structure

910463-68-2
C187H291N45O59
4113.58 g/mol
White to off-white lyophilized powder
Laboratory Tests & Certificates
01572028
Prod. January 29, 2026
Exp. July 14, 2028







